Motion of tympanic membrane in guinea pig otitis media model measured by scanning laser Doppler vibrometry
Otitis media (OM) is an inflammatory or infectious disease of the middle ear. Acute otitis
media (AOM) and otitis media with effusion (OME) are the two major types of OM. However,
the tympanic membrane (TM) motion differences induced by AOM and OME have not been
quantified in animal models in the literature. In this study, the guinea pig AOM and OME
models were created by transbullar injection of Streptococcus pneumoniae type 3 and
lipopolysaccharide, respectively. To explore the effects of OM on the entire TM vibration, the …
media (AOM) and otitis media with effusion (OME) are the two major types of OM. However,
the tympanic membrane (TM) motion differences induced by AOM and OME have not been
quantified in animal models in the literature. In this study, the guinea pig AOM and OME
models were created by transbullar injection of Streptococcus pneumoniae type 3 and
lipopolysaccharide, respectively. To explore the effects of OM on the entire TM vibration, the …
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