Chemical approaches for the construction of multi-enzyme reaction systems

S Schoffelen, JCM Van Hest - Current opinion in structural biology, 2013 - Elsevier
… Here, we will focus on the application of bioconjugation chemistry in the creation of multi-enzyme
systems. In the past years, the collection of chemical methods to covalently couple …

Multi-enzyme systems: bringing enzymes together in vitro

S Schoffelen, JCM van Hest - Soft Matter, 2012 - pubs.rsc.org
… catalyzes the last two reactions in tryptophan biosynthesis. The two steps are catalyzed by
two separate subunits (α and β), which combine to form a stable multi-enzyme complex (α 2 β …

Bioinspired construction of multi-enzyme catalytic systems

J Shi, Y Wu, S Zhang, Y Tian, D Yang… - Chemical Society …, 2018 - pubs.rsc.org
… catalysis occupies a unique and indispensable position in the realm of biological reactions
… in vivo multi-enzyme reactions (MERs), which have been applied to construct multi-enzyme

Multi-enzyme systems in flow chemistry

P Fernandes, CCCR de Carvalho - Processes, 2021 - mdpi.com
… that is advantageous in enzymatic reactions, but parameters … in flow reactors allows
multi-enzyme reactions to be carry out … the reactors and to perform the reactions in the presence of …

Overview on reactions with multi-enzyme systems

Z Findrik, Đ Vasić-Rački - Chemical and biochemical engineering …, 2009 - hrcak.srce.hr
… Systems with two enzymes are the most frequently investigated among all multi-enzyme
systems … Reactions with three-enzyme systems Many multi-enzyme reactions run simultaneously …

Strategies and perspectives of assembling multi-enzyme systems

SZ Wang, YH Zhang, H Ren, YL Wang… - Critical Reviews in …, 2017 - Taylor & Francis
… time, competing side reactions and enhancement of initial reaction rates has been
reviewed [… initial reaction rate of the multi-enzyme system to free enzymes in the solution [Citation60]. …

Multi-enzyme activity nanozymes for biosensing and disease treatment

L Su, S Qin, Z Xie, L Wang, K Khan, AK Tareen… - Coordination Chemistry …, 2022 - Elsevier
… in the field of multi-enzyme activity nanozymes. We systematically introduced the detailed
classification of multi-enzyme activity nanozymes based on the redox reaction, followed by a …

Multi‐enzymatic cascade reactions: overview and perspectives

E Ricca, B Brucher… - Advanced Synthesis & …, 2011 - Wiley Online Library
… In this section, multi-enzyme and chemo-enzymatic reactions are discussed from the point
of view of bioprocess engineering in order to put in evidence their strong and weak points and …

Multienzyme Cascade Reactions in Metal‐organic Frameworks

J Liang, K Liang - The Chemical Record, 2020 - Wiley Online Library
Multienzyme cascade reactions are indispensable in … Multienzyme cascade reactions in
MOFs have recently … This Personal Account discusses the different strategies for multienzyme

A multi-enzyme cascade reaction for the production of 2′ 3′-cGAMP

M Becker, P Nikel, JN Andexer, S Lütz, K Rosenthal - Biomolecules, 2021 - mdpi.com
… was investigated by using a multi-enzyme cascade reaction with adenosine as initial …
catalyzed reaction steps from adenosine as well as polyP and GTP in a biocatalytic one-pot reaction