Multiscale in silico lung modeling strategies for aerosol inhalation therapy and drug delivery

P Koullapis, B Ollson, SC Kassinos… - Current opinion in …, 2019 - Elsevier
Inhalation therapy is a hallmark of modern respiratory medicine. Over recent years,
computational fluid-particle dynamics (CFPD) simulations of respiratory airflows and aerosol
deposition in the lungs have rapidly developed into an increasingly mature research field in
the biomedical engineering realm, owing, among others, to tremendous advances in
computational capabilities and available resources. Despite such progress, the intrinsic
anatomical and physiological complexity of the lungs prevents the straightforward …
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