The incidence of acute pancreatitis (AP) is increasing globally and mortality could be high
among patients with organ failure and infected necrosis. The predominant factors
responsible for the morbidity and mortality of AP are systemic inflammatory response
syndrome and multiorgan dysfunction. Even though preclinical studies have shown
antisecretory agents (somatostatin), antioxidants (S-adenosyl methionine [SAM], selenium),
protease inhibitors, platelet activating factor inhibitor (Lexipafant), and anti-inflammatory …