… on properties of different forms of SCR7. Here, we give a succinct account on the use of
SCR7 and its different forms in CRISPR-Cas system, highlighting their chemical properties and …

… binds to the DNA-binding transcription factor RUNX1 to form … as, type II collagen (Col II),
aggrecan, and tissue inhibitors of … Their overall data suggested that KGN could be a potent tool …

… SCR7 is also used as a potent biochemical inhibitor of NHEJ, which has found its application
in improving genome editing using a CRISPR-… but SCR7 has also shown promising results. …

… , it has arisen as a significant life-threatening disease in men at an older age. At the early
onset of illness when it is in localized form, … Our analysis and inter- pretation are promising for …

… Other inhibitors did not show any inhibition of … All inhibitors except 4-methyl pyrazole showed
inhibitory effects on tanzisertib formation from CC-418424 and the percentage of inhibition …

Background: Elexacafior/tezacafior/ivacafior is a highly effective modulator that improves
function of the cys-tic fibrosis transmembrane conductance regulator (CFTR) protein, resulting …

… precision genome editing and provided a novel promising avenue … efficiency of genome
editing by either suppressing NHEJ or … by combining SCR7 with enhancing genome engineering …

… CRISPR-Cas9 has emerged as a powerful tool for genome … Our study suggests promising
applications in genome editing … overexpression and NHEJ inhibition by SCR7 increased HR …

… promising approaches to enhance CRISPR/Cas9 genome-… of SCR7 on CRISPR/Cas9-induced
HDR genome editing were … NHEJ rate by ∼ 2.3-fold with SCR7 treatment using CRISPR/…

… -Cas9, is a powerful tool for research and a promising approach for therapeutic treatment of
human disease. One strategy for efficient genome editing … SCR7 inhibits NHEJ to rebalance …