… the multi-ethnic NHLBI Trans-Omics for Precision Medicine (TOPMed) program to impute …
We demonstrated that using TOPMed sequencing data as the imputation reference panel …

… Like other clinical hematologic laboratory measures, PLT and MPV are highly heritable, with
… Studies of PLT and MPV in a significant number of individuals without known hematological …

… We combined whole genome sequencing (WGS) data from 23,732 participants from 10
NHLBI Trans-Omics for Precision Medicine (TOPMed) Program multi-ethnic studies to identify …

… A key goal of the TOPMed program is to identify genetic risk … of phenotype data in TOPMed
includes a collaborative … with examples of applications to TOPMed study data. We also …

… Many common and rare variants associated with hematologic traits have been discovered …
and the X chromosome in the Trans-Omics for Precision Medicine (TOPMed) program, which …

… of mortality risk which includes several hematological variables such as white blood cell …
in myeloproliferative neoplasm, a hematological malignancy which is strongly associated with …

… the NHLBI Trans-Omics for Precision Medicine (TOPMed) … GWAS datasets imputed to the
TOPMed reference panel. Most of … architecture of quantitative hematologic traits and suggest a …

… clonal hematologic disorders based on the absence of cytopenia, dysplasia, and neoplasia.
We considered whether there were sub-clinical hematologic … Notably, RDW is a hematologic …

… the NHLBI Trans-Omics for Precision Medicine (TOPMed) … In the general population,
hematologic quantitative traits are … variants have been associated with hematologic traits; …

… the NHLBI Trans-Omics for Precision Medicine (TOPMed) … In the general population,
hematologic quantitative traits are … variants have been associated with hematologic traits; …