NO-induced migraine attack: strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release

G Juhasz, T Zsombok, EA Modos, S Olajos, B Jakab… - Pain, 2003 - Elsevier
The aim of the present study was to investigate changes in the plasma calcitonin gene-
related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT)
content during the immediate headache and the delayed genuine migraine attack provoked
by nitroglycerin. Fifteen female migraineurs (without aura) and eight controls participated in
the study. Sublingual nitroglycerin (0.5 mg) was administered. Blood was collected from the
antecubital vein four times: 60 min before and after the nitroglycerin application, and 60 and …
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