A Lanza, E Margheritis, E Mugnaioli,
V Cappello… - IUCrJ, 2019 - journals.iucr.org
Recent advances in 3D electron diffraction have allowed the structure determination of
several model proteins from submicrometric crystals, the unit-cell parameters and structures
of which could be immediately validated by known models previously obtained by X-ray
crystallography. Here, the first new protein structure determined by 3D electron diffraction
data is presented: a previously unobserved polymorph of hen egg-white lysozyme. This
form, with unit-cell parameters a= 31.9, b= 54.4, c= 71.8 Å, β= 98.8°, grows as needle …