Several microbes, including Staphylococcus epidermidis (S. epidermidis), a Gram-positive
bacterium, live inside the human nasal cavity as commensals. The role of these nasal
commensals in host innate immunity is largely unknown, although bacterial interference in
the nasal microbiome may promote ecological competition between commensal bacteria
and pathogenic species. We demonstrate here that S. epidermidis culture supernatants
significantly suppressed the infectivity of various influenza viruses. Using high-performance …