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Neuroprotective Effect of Phlorotannin Isolated from Ishige okamurae Against H2O2-Induced Oxidative Stress in Murine Hippocampal Neuronal Cells, HT22

SJ Heo, SH Cha, KN Kim, SH Lee, G Ahn… - Applied biochemistry …, 2012 - Springer
The present study is designed to investigate the neuroprotective effect of a kind of
phlorotannins, diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae against
hydrogen peroxide (H 2 O 2)-induced oxidative stress in murine hippocampal neuronal
cells, HT22. H 2 O 2 treatment induced neurotoxicity, whereas DPHC prevented cells from H
2 O 2-induced damage then restoring cell viability was significantly increased. DPHC slightly
reduced the expression of Bax induced by H 2 O 2 but recovered the expression of Bcl-xL as …
被引用次数：63 相关文章 所有 12 个版本

Neuroprotective effect of phlorotannin isolated from Ishige okamurae against H2O2-induced oxidative stress in murine hippocampal neuronal cells, HT22.

HSJ Heo SooJin, SH Cha, KKN Kim KilNam… - 2012 - cabidigitallibrary.org
The present study is designed to investigate the neuroprotective effect of a kind of
phlorotannins, diphlorethohydroxycarmalol (DPHC) isolated from Ishige okamurae against
hydrogen peroxide (H2O2)-induced oxidative stress in murine hippocampal neuronal cells,
HT22. H2O2 treatment induced neurotoxicity, whereas DPHC prevented cells from H2O2-
induced damage then restoring cell viability was significantly increased. DPHC slightly
reduced the expression of Bax induced by H2O2 but recovered the expression of Bcl-xL as …
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