nitive theory of mind” refers to our ability to make inferences regarding other people’s beliefs,“affective theory of mind” refers to the inferences one makes regarding others’ emotions. While “cognitive theory of mind” is very similar to “cognitive empathy,”“affective theory of mind” may be related to both cognitive and affective empathy. It appears that the centrality of emotion distinguishes between the affective and cognitive aspects of empathy and theory of mind. Cognitive empathy has been shown to depend on intact ventromedial prefrontal cortical functioning. 14 Interestingly, ventromedial prefrontal cortical dysfunction has been reported in bipolar disorder. 15 Furthermore, recent research indicates that many of the core features of bipolar disorder overlap with those known to characterize frontal lobe syndrome. 16 Additionally, it has been suggested that bipolar disorder patients show impairment in frontal neurocognitive tasks that involve cognitive flexibility. 17 On the other hand, the neuroanatom-