Neutralizing possibilities of whole virion and mRNA vaccine triggered antibodies of Wuhan strain of SARS-CoV-2 with receptor binding domains of spike proteins of …
Mutations in the receptor binding domain (RBD) of SARS-CoV-2 spike protein have given
birth to the new variants of concern viz. Delta and Omicron strain. As we are using vaccines
which are either mRNA of spike protein of Wuhan strain or its whole virion vaccine, these
vaccines will trigger antibodies to be able to bind with the epitopes of spike protein of Wuhan
strain. There appears a need to study whether vaccine generated circulating neutralizing
antibodies in vaccinated people are able to neutralize the receptor binding domain of spike …
birth to the new variants of concern viz. Delta and Omicron strain. As we are using vaccines
which are either mRNA of spike protein of Wuhan strain or its whole virion vaccine, these
vaccines will trigger antibodies to be able to bind with the epitopes of spike protein of Wuhan
strain. There appears a need to study whether vaccine generated circulating neutralizing
antibodies in vaccinated people are able to neutralize the receptor binding domain of spike …
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