[HTML][HTML] Neutrophil expression and infiltration into Crohn′ s intestine
MA Alzoghaibi - Saudi Journal of Gastroenterology, 2005 - journals.lww.com
Crohn′ s disease (CD) is a chronic inflammatory bowel disease (IBD) of unknown etiology.
The main pathological feature of IBD is transmural infiltration of polymorphonuclear
neutrophils (PMN) and mononuclear cells associated with smooth muscle cell proliferation,
accumulation of collagen, thickening and stenosis. While the etiology of Crohn′ s disease
remains unknown, increased levels of proinflammatory cytokines, such as IL-1, IL-6, IL-8 and
TNF in the inflamed bowel probably play a major role in the tissue injury and fibrosis that …
The main pathological feature of IBD is transmural infiltration of polymorphonuclear
neutrophils (PMN) and mononuclear cells associated with smooth muscle cell proliferation,
accumulation of collagen, thickening and stenosis. While the etiology of Crohn′ s disease
remains unknown, increased levels of proinflammatory cytokines, such as IL-1, IL-6, IL-8 and
TNF in the inflamed bowel probably play a major role in the tissue injury and fibrosis that …
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