The advancement of new 2D-TMDC material semiconductors remains a prominent research area as the number of scientific applications grows. One Of those materials," molybdenum disulfide," has newly investigated to graphene & Si material alternative. Single-layer molybdenum disulfide (SLMoS 2) is used as substitute for graphene & other semiconductor appliances with a high capability of practices in nano-electronic, energy-storing, photocatalysts, optical sensors, biosensors & Electro-Chemical biosensors. It's working even in widespread variety of energy-related applications, including batteries, solar cells, microwaves, & Terahertz. Furthermore, future hopeful material in nano-scale fields, having additional opportunities in spintronics & magneto-resistance. Many research papers have published papers on the Evolution & Application of MoS 2 materials but here in the paper, will give a complete depth comprehensive examination & analysis of the evolution of various 2D materials, starting with their state of requirement, formation, properties, applications, future challenges along with the various comparison simulation results.