[HTML][HTML] Novel binding studies of human serum albumin with trans-feruloyl maslinic acid

R Subramanyam, M Goud, B Sudhamalla… - … of Photochemistry and …, 2009 - Elsevier
Human serum albumin (HSA) is a predominant protein in the blood. Most drugs can bind to
HSA and be transported to target locations of the body. For this study, we have extracted 3-
trans-feruloyl maslinic acid (FMA) from the medicinal plant Tetracera asiatica, its a non-
fluorescent derivative have potent anti-cancer, anti-HIV, anti-diabetic, and anti-inflammatory
activities. The binding constant of the compound with HSA, calculated from fluorescence
data, was found as KFMA= 1.42±0.01× 108M− 1, which corresponds to 10.9 kcal M− 1 of …

Novel binding studies of human serum albumin with trans-feruloyl maslinic acid.

RS Rajagopal Subramanyam, MG Mahesh Goud… - 2009 - cabidigitallibrary.org
Human serum albumin (HSA) is a predominant protein in the blood. Most drugs can bind to
HSA and be transported to target locations of the body. For this study, we have extracted 3-
trans-feruloyl maslinic acid (FMA) from the medicinal plant Tetracera asiatica, its a non-
fluorescent derivative have potent anti-cancer, anti-HIV, anti-diabetic, and anti-inflammatory
activities. The binding constant of the compound with HSA, calculated from fluorescence
data, was found as K FMA= 1.42±0.01× 108 M-1, which corresponds to 10.9 kcal M-1 of free …
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