Novel glycoconjugated squaraine dyes for selective optical imaging of cancer cells

M Shimi, V Sankar, MKA Rahim, PR Nitha… - Chemical …, 2017 - pubs.rsc.org
M Shimi, V Sankar, MKA Rahim, PR Nitha, S Das, KV Radhakrishnan, KG Raghu
Chemical Communications, 2017pubs.rsc.org
… Herein, we describe the design, synthesis and application of Sq-glucose conjugates for
tumor optical imaging. … In conclusion, we have designed and synthesized novel
carbohydrate appended Sq dyes for optical imaging of tumor cells. Cancer cell selectivity was
achieved with Sq-glucose conjugates by targeting the Warburg effect. The unsymmetrical Sq …
Novel glycoconjugated squaraine dyes were synthesized, which exhibited excellent internalization in tumor cells and are potent fluorogenic imaging probes for tumor selective optical imaging.
The Royal Society of Chemistry
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