Neurodegeneration, the slow and progressive dysfunction and loss of neurons and axons in
the central nervous system, is the primary pathological feature of acute and chronic
neurodegenerative conditions such as Alzheimer's disease (AD) and Parkinson's disease
(PD). Neurodegenerative diseases affect not only the life quality of the aging population but
also their life spans. Aging is associated with a tissue degeneration phenotype marked by
loss of tissue regenerative capacity. In this chapter, we propose that the pathophysiological …