OCT4B1, a novel spliced variant of OCT4, is highly expressed in gastric cancer and acts as an antiapoptotic factor
The octamer‐binding transcription factor 4 (OCT4) is involved in regulating pluripotency and
self‐renewal maintenance of embryonic stem cells. Recently, misexpression of OCT4 has
been also reported in some adult stem as well as cancer cells; a finding which is still
controversial. In addition to the previously described spliced variants of the gene (eg,
OCT4A and OCT4B), we have recently identified a novel variant of the gene, designated as
OCT4‐B1. In this study, we investigated a potential expression and function of OCT4B1 in a …
self‐renewal maintenance of embryonic stem cells. Recently, misexpression of OCT4 has
been also reported in some adult stem as well as cancer cells; a finding which is still
controversial. In addition to the previously described spliced variants of the gene (eg,
OCT4A and OCT4B), we have recently identified a novel variant of the gene, designated as
OCT4‐B1. In this study, we investigated a potential expression and function of OCT4B1 in a …
OCT4B1, A Novel Spliced Variant of OCT4, Is Highly Expressed in Gastric Cancer and Acts As An Antiapoptotic Factor.
Objective: The octamer-binding transcription factor 4 (OCT4) is involved in regulating
pluripotency and self-renewal maintenance of embryonic stem cells. Recently,
misexpression of OCT4 has been also reported in some adult stem as well as cancer cells; a
finding which is still controversial. In addition to the previously described spliced variants of
the gene (eg, OCT4A and OCT4B), we have recently identified a novel variant of the gene,
designated as OCT4-B1. Materials and Methods: In this study, we investigated a potential …
pluripotency and self-renewal maintenance of embryonic stem cells. Recently,
misexpression of OCT4 has been also reported in some adult stem as well as cancer cells; a
finding which is still controversial. In addition to the previously described spliced variants of
the gene (eg, OCT4A and OCT4B), we have recently identified a novel variant of the gene,
designated as OCT4-B1. Materials and Methods: In this study, we investigated a potential …
以上显示的是最相近的搜索结果。 查看全部搜索结果