[HTML][HTML] OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records

…, ST Weiss, NJW Rattray, VN Gladyshev, E Karlson… - bioRxiv, 2023 - ncbi.nlm.nih.gov
… , the first DNA methylation-based multi-omic agingOMICmAge, while further substantiating
the biological relevance and value of integrating multiple omic data into one biological aging

OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records

…, V Gladyshev, E Karlson, C Wheelock, E Mathé… - …, 2024 - journals.physiology.org
Biological aging is a multifactorial process involving complex … a robust, predictive biological
aging phenotype, EMRAge, that … , generating DNAmEMRAge and OMICmAge, respectively. …

[PDF][PDF] OMICmAge: An integrative multi-omics approach to quantify biological age with electronic

MS Qingwen Chen, VB Dwaraka… - …, 2021 - storage.prod.researchhub.com
biological age: 1) EMRAge, a clinically-based and versatile death mortality predictor that
can be broadly recapitulated across EMRs; 2) DNAmEMRAge, a DNA methylation aging …

Multidimensional Epigenetic Clocks Demonstrate Accelerated Aging Across Physiological Systems in Schizophrenia: A Meta-Analysis

ZM Harvanek, R Sehgal, D Borrus, J Kasamoto… - medRxiv, 2024 - medrxiv.org
… clocks that split aging into multiple scores to analyze biological aging in schizophrenia. These
OMICmAge: An integrative multi-omics approach to quantify biological age with electronic

Multi-omics Analysis Reveals Biomarkers that Contribute to Biological Age Rejuvenation in Response to Therapeutic Plasma Exchange

…, ZS Yuksel, C Roska-Pamaong, B Schilling, E Verdin… - medRxiv, 2024 - medrxiv.org
… greater decrease in biological age with an average BA rejuvenation of 1.32 years (p = 5.7e-03), …
Epigenomics data was used to calculate the differences in BA induced by the treatments. …

NMR metabolomics-guided DNA methylation mortality predictors

…, M Ghanbari, L Franke, JM Geleijnse, E Boersma… - …, 2024 - thelancet.com
… Leveraging multi-omics data in four Dutch population … of biological age would allow to
quantify the vulnerability to acute and chronic diseases irrespective of an individual's calendar age

The Impact of a Natural Ingredients based Intervention Targeting the Nine Hallmarks of Aging on DNA methylation

N Carreras-Gallo, R Dargham, S Thorpe, S Warren… - bioRxiv, 2024 - biorxiv.org
… of aging, known as epigenetic clocks, measure biological age … For OMICmAge acceleration,
the SRW cohort exhibited a mean … Our results demonstrate a reversal of biological aging in …

Ketamine treatment effects on DNA methylation and Epigenetic Biomarkers of aging

K Dawson, AMJM Carangan, J Klunder… - medRxiv, 2024 - medrxiv.org
… We observed a reduction in epigenetic age in the OMICmAge… ) to quantify biological changes
that occur when individuals age to … in clinical variables and biological age, we conducted a …

Integrative epigenetics and transcriptomics identify aging genes in human blood

M Moqri, JR Poganik, C Herzog, K Ying, Q Chen… - bioRxiv, 2024 - biorxiv.org
biological age predictions 2, yet few studies to date have investigated direct links between
age-related DNAm changes in blood, and highlight the potential for multi-omics approaches

[HTML][HTML] Longevity biotechnology: Bridging AI, biomarkers, geroscience and clinical applications for healthy longevity

…, E Morgen, E Verdin, E Vernet, E Pinilla… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
… -measurement-based biological age predictors have been … Similarly, a new OMICmAge
integrates multi-omics data, including … Furthermore, employing AI to integrate multi-omics data for …