Ocular instillation of vitamin A–coupled liposomes containing HSP47 siRNA ameliorates dry eye syndrome in chronic GVHD
H Ohigashi, D Hashimoto, E Hayase… - Blood …, 2019 - ashpublications.org
… We explored the role of heat shock protein 47 (HSP47) in ocular GVHD … vitamin A–coupled
liposomes containing HSP47 small interfering RNA (siRNA) against HSP47 (VA-lip HSP47). …
liposomes containing HSP47 small interfering RNA (siRNA) against HSP47 (VA-lip HSP47). …
Ocular instillation of vitamin A-coupled liposomes containing HSP47 siRNA ameliorates dry eye syndrome in chronic graft-versus-host disease
H Ohigashi, D Hashimoto, S Takahashi… - Biology of Blood and …, 2019 - Elsevier
… (VA-lip HSP47) ameliorates skin and salivary gland fibrosis in chronic GVHD (… the role of
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …
[HTML][HTML] Nanotechnology-based Therapeutic Strategies for Dry Eye Disease
AK Philip - Journal of Exploratory Research in Pharmacology, 2023 - xiahepublishing.com
… vitamin A-coupled liposomes (VA-lip) containing heat shock protein 47 (HSP47) for a
formulation (VA-lip HSP47), … Additionally, ocular instillation of VA-lip HSP47 also ameliorated …
formulation (VA-lip HSP47), … Additionally, ocular instillation of VA-lip HSP47 also ameliorated …
siRNA therapeutics in ocular diseases
J Moreno-Montañés, AM Bleau, T Martínez… - … and Delivery of SiRNA …, 2021 - Springer
… ) is currently under preclinical studies for the treatment of dry eye disease (DED) associated
… ocular topical instillation of this HSP47-siRNA encapsulated in Vitamin A-coupled liposomes …
… ocular topical instillation of this HSP47-siRNA encapsulated in Vitamin A-coupled liposomes …
Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection
JJ López-Cano… - Expert opinion on …, 2021 - Taylor & Francis
… mm after 1 month of treatment, obtained an amelioration in the rate of recovery and a decrease
in … SiRNA liposomes tackling heat shock protein 47 (HSP47) combined with vitamin A are …
in … SiRNA liposomes tackling heat shock protein 47 (HSP47) combined with vitamin A are …
Inhibition of heat shock protein 47 suppressed collagen production in Tenon's capsule fibroblasts
W Wang - Folia Histochemica et Cytobiologica, 2023 - journals.viamedica.pl
… characterized by elevation of intraocular pressure (IOP) … HSP47 siRNA reduces the levels
of collagen I in RTF cells. These in vitro results indicate the possibility to use HSP47 siRNA …
of collagen I in RTF cells. These in vitro results indicate the possibility to use HSP47 siRNA …
[HTML][HTML] High levels of heat shock protein 47 in the aqueous humor of patients with acute primary angle closure
W Wang, H Yu, X Yang, Q Xu, H Yan, J Liu - Ophthalmic Research, 2023 - karger.com
… [19] explored vitamin A-coupled liposomes containing HSP47 small interfering RNA, which
interferes with HSP47, to treat dry eye syndrome of ocular chronic graft-versus-host disease …
interferes with HSP47, to treat dry eye syndrome of ocular chronic graft-versus-host disease …
HSP47: a potential target for fibrotic diseases and implications for therapy
PS Bellaye, O Burgy, P Bonniaud… - Expert opinion on …, 2021 - Taylor & Francis
… uptake of vitamin A and coupling liposomes containing anti-HSP47 siRNA with vitamin A …
As a consequence, HSP47 siRNA delivery through vitamin A liposomes could potentially be …
As a consequence, HSP47 siRNA delivery through vitamin A liposomes could potentially be …
[HTML][HTML] Optimizing c-type lectin-like molecule 1 (Cll-1) directed car T cell therapy of acute myeloid leukemia
… systemic administration of vitamin A-coupled liposomes carrying HSP47 siRNA (VA-lip …
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …
[HTML][HTML] Modeling Sézary Syndrome for Immunophenotyping and Anti-Tumor Effect of Ucart and Long-Acting Interleukin-7 Combination Therapy
KW Staser, M Cooper, J Choi, A Chukka… - Biology of Blood and …, 2019 - Elsevier
… systemic administration of vitamin A-coupled liposomes carrying HSP47 siRNA (VA-lip …
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …
HSP47 in ocular GVHD and tested if ocular instillation of VA-lip HSP47 could ameliorate dry eye …