On the relationship between diabetes and obstructive sleep apnea: evolution and epigenetics

NRC Wilson, OJ Veatch, SM Johnson - Biomedicines, 2022 - mdpi.com
This review offers an overview of the relationship between diabetes, obstructive sleep apnea
(OSA), obesity, and heart disease. It then addresses evidence that the traditional
understanding of this relationship is incomplete or misleading. In the process, there is a brief
discussion of the evolutionary rationale for the development and retention of OSA in light of
blood sugar dysregulation, as an adaptive mechanism in response to environmental
stressors, followed by a brief overview of the general concepts of epigenetics. Finally, this …

[PDF][PDF] On the Relationship between Diabetes and Obstructive Sleep Apnea: Evolution and Epigenetics. Biomedicines 2022, 10, 668

NRC Wilson, OJ Veatch, SM Johnson - 2022 - academia.edu
This review offers an overview of the relationship between diabetes, obstructive sleep apnea
(OSA), obesity, and heart disease. It then addresses evidence that the traditional
understanding of this relationship is incomplete or misleading. In the process, there is a brief
discussion of the evolutionary rationale for the development and retention of OSA in light of
blood sugar dysregulation, as an adaptive mechanism in response to environmental
stressors, followed by a brief overview of the general concepts of epigenetics. Finally, this …
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