[PDF][PDF] On the role of noradrenergic system in PTSD and related sleep disturbances. The use of terazosin in PTSD related nightmares: a case report

M Salviati, M Pallagrosi, G Valeriani, C Carlone… - Clin Ter, 2013 - researchgate.net
M Salviati, M Pallagrosi, G Valeriani, C Carlone, L Todini, M Biondi
Clin Ter, 2013researchgate.net
In PTSD sleep disorders represent an important symptoms dimension, which is associated
with more severe PTSD, and increased risk of relapse. The basic treatment for PTSD in not
always associated to an improvement of sleep disturbances and nightmares. Alpha-
blockers, and more specifically Prazosin, have shown a specific action on sleep disorders in
PTSD. We report the clinical case of a young women with PTSD, who was suffering from
severe sleep disorder and distressing nightmare. The patient was treated with Terazosin, a …
Abstract
In PTSD sleep disorders represent an important symptoms dimension, which is associated with more severe PTSD, and increased risk of relapse. The basic treatment for PTSD in not always associated to an improvement of sleep disturbances and nightmares. Alpha-blockers, and more specifically Prazosin, have shown a specific action on sleep disorders in PTSD. We report the clinical case of a young women with PTSD, who was suffering from severe sleep disorder and distressing nightmare. The patient was treated with Terazosin, a conger of Prazosin, and has shown symptom remission. Further studies on the use of alpha-blokers might reveal new therapeutic options in PTSD. Clin Ter 2013; 164 (2): 1-3. doi: 10.7417/CT. 2013.1501
researchgate.net
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