Optimization and evaluation of silk fibroin-chitosan freeze-dried porous scaffolds for cartilage tissue engineering application

V Vishwanath, K Pramanik, A Biswas - Journal of Biomaterials …, 2016 - Taylor & Francis
Silk fibroin/chitosan blend has been reported to be an attractive biomaterial that provides a
3D porous structure with controllable pore size and mechanical property suitable for tissue
engineering applications. However, there is no systematic study for optimizing the ratio of
silk fibroin (SF) and chitosan (CS) which seems to influence the scaffold property to a great
extent. The present research, therefore, investigates the effect of blend ratio of SF and CS on
scaffold property and establishes the optimum value of blend ratio. Among the various …

Optimization and evaluation of silk fibroin-chitosan freeze-dried porous scaffolds for cartilage tissue engineering application.

VV Varshini Vishwanath, KP Krishna Pramanik… - 2016 - cabidigitallibrary.org
Silk fibroin/chitosan blend has been reported to be an attractive biomaterial that provides a
3D porous structure with controllable pore size and mechanical property suitable for tissue
engineering applications. However, there is no systematic study for optimizing the ratio of
silk fibroin (SF) and chitosan (CS) which seems to influence the scaffold property to a great
extent. The present research, therefore, investigates the effect of blend ratio of SF and CS on
scaffold property and establishes the optimum value of blend ratio. Among the various …
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