Ordered deployment of distinct ciliary beating machines in growing axonemes of vertebrate multiciliated cells

C Lee, Y Ma, F Tu, JB Wallingford - Differentiation, 2023 - Elsevier
The beating of motile cilia requires the coordinated action of diverse machineries that
include not only the axonemal dynein arms, but also the central apparatus, the radial
spokes, and the microtubule inner proteins. These machines exhibit complex radial and
proximodistal patterns in mature axonemes, but little is known about the interplay between
them during motile ciliogenesis. Here, we describe and quantify the relative rates of
axonemal deployment for these diverse cilia beating machineries during the final stages of …
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