Nicotine addiction, the result of tobacco use, leads to over six million premature deaths
world-wide per year, a number that is expected to increase by a third within the next two
decades. While more than half of smokers want and attempt to quit, only a small percentage
of smokers are able to quit without pharmacological interventions. Therefore, over the past
decades, researchers in academia and the pharmaceutical industry have focused their
attention on the development of more effective smoking cessation therapies, which is now a …