Osteopontin (OPN) is a highly phosphorylated glycophosphoprotein having acidic characteristics
and rich in aspartic acid. OPN, a multifunctional protein, has important functions on …

Osteopontin (OPN) is a highly phosphorylated sialoprotein that is a prominent component of
the mineralized extracellular matrices of bones and teeth. OPN is characterized by the …

In this review most of the various known, suspected, or postulated functions of osteopontin,
a secreted highly acidic phosphoprotein, are discussed in terms of what we currently know …

… osteopontin is an important component in the formation of bone. The level of synthesis of
osteopontin by … In addition to bone cells, osteopontin is synthesized by extraosseous cells in the …

Publisher Summary Osteopontin (OPN) is one of the noncollagenous proteins present in
bone matrix. The presence of OPN in various organs, including those with and without matrix, …

Osteopontin (OPN) is a matricellular protein that mediates diverse biological functions. OPN
is involved in normal physiological processes and is implicated in the pathogenesis of a …

A matricellular protein, osteopontin (OPN), is expressed in response to mechanical stress
and similar stimuli in the heart, integrates the inter-ECM signal transduction network of …

… Osteopontin expression is indicated by brown staining and was immunolocalized using an
anti-osteopontin … A, Healthy ovarian surface epithelial cells with no expression of osteopontin. …

Since its first identification as a transformation-associated protein, osteopontin (OPN) has
been recognised as important in the processes of tumorigenicity and metastasis. Here, we …

Osteopontin (OPN) is a multifunctional protein, and although highly expressed in bone, it is
also expressed by various cell types including macrophages, endothelial cells, smooth …