Distortion-product otoacoustic emissions as a screening tool for noise-induced hearing loss

L Marshall, JAL Miller, LM Heller - Noise and health, 2001 - journals.lww.com
measure be used to predict susceptibility to NIHL? Evoked otoacoustic emissions (EOAEs)
depend on normal outer hair … changes, pre-clinical hearing loss, and susceptibility to NIHL …

Otoacoustic emissions versus audiometry in monitoring hearing loss after long-term noise exposure–a systematic review

HW Helleman, H Eising, J Limpens… - Scandinavian journal of …, 2018 - JSTOR
hearing impairment, called noise-induced hearing loss (NIHL)… noise-induced damage results
in loss of hearing sensitivity … to detect so-called preclinical damage. There are two aspects …

Evidence of noise-induced subclinical hearing loss using auditory brainstem responses and objective measures of noise exposure in humans

E Skoe, J Tufts - Hearing research, 2018 - Elsevier
… of objective noise measurements, longitudinal assessments, … of noise-induced hearing loss
in humans at both pre-clinical … The effect of low level acoustic stimulation on susceptibility to …

Prevention of noise-induced hearing loss using investigational medicines for the inner ear: Previous trial outcomes should inform future trial design

CG Le Prell - Antioxidants & redox signaling, 2022 - liebertpub.com
… Changes in otoacoustic emission (OAE) amplitude were … The variation across preclinical
research studies has since … for EHF sensitivity, are more vulnerable to noise-induced injury, …

Drug development for noise-induced hearing loss

I Varela-Nieto, S Murillo-Cuesta, M Calvino… - Expert opinion on …, 2020 - Taylor & Francis
… Researchers need to develop standardized preclinical models … Otoacoustic emissions and
high-frequency audiometry are … and shows greater susceptibility to noise-induced injury than …

Noise-induced hearing loss and its prevention: Current issues in mammalian hearing

CG Le Prell, TA Hackett, R Ramachandran - Current opinion in physiology, 2020 - Elsevier
otoacoustic emissions (DPOAEs), which measure outer hair cell … assessments that form a
bridge to human susceptibility. … in various stages ranging from pre-clinical to Phase I or even …

Translating animal models to human therapeutics in noise-induced and age-related hearing loss

SG Kujawa, MC Liberman - Hearing research, 2019 - Elsevier
… of these forms of hearing loss, and preclinical studies have led to … using distortion product
otoacoustic emissions (DPOAEs), … progression of OHC-based sensitivity losses with age was …

Development of drugs for noise-induced hearing loss

ED Lynch, J Kil, CG Le Prell - … in Audiology, Neurotology, and the Hearing …, 2016 - Springer
… in preclinical tests, whereas human studies typically assess pure-tone threshold sensitivity
… [spontaneous otoacoustic emission (SOAE)], evoked by a transient sound [transient evoked …

Current insights in noise-induced hearing loss: a literature review of the underlying mechanism, pathophysiology, asymmetry, and management options

TN Le, LV Straatman, J Lea… - … of otolaryngology-head …, 2017 - journals.sagepub.com
hearing loss, leading to an increased susceptibility to noise … Otoacoustic emissions have
the necessary features to serve … NIHL at an earlier, “pre-clinical” stage, although more data is …

Otoacoustic emissions in ears with hearing loss

R Probst, BL Lonsbury-Martin, GK Martin… - American journal of …, 1987 - Elsevier
… to increase the microphone's sensitivity. To avoid amplifier … between the group with
noise-induced hearing loss (NI) … , at a preclinical stage, noise-induced, sensory-cell damage to …