Overcoming toxicity and side-effects of lipid-lowering therapies

MJ Wilkinson, LJ Laffin, MH Davidson - Best Practice & Research Clinical …, 2014 - Elsevier
Lowering serum lipid levels is part of the foundation of treating and preventing clinically
significant cardiovascular disease. Recently, the American Heart Association/American
College of Cardiology released cholesterol guidelines which advocate for high efficacy
statins rather than LDL-c goals for five patient subgroups at high risk for cardiovascular
disease. Therefore, it is critical that clinicians have an approach for managing side-effects of
statin therapy. Statins are associated with myopathy, transaminase elevations, and an …
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