PPLine: an automated pipeline for SNP, SAP, and splice variant detection in the context of proteogenomics
GS Krasnov, AA Dmitriev… - Journal of proteome …, 2015 - ACS Publications
The fundamental mission of the Chromosome-Centric Human Proteome Project (C-HPP) is
the research of human proteome diversity, including rare variants. Liver tissues, HepG2
cells, and plasma were selected as one of the major objects for C-HPP studies. The
proteogenomic approach, a recently introduced technique, is a powerful method for
predicting and validating proteoforms coming from alternative splicing, mutations, and
transcript editing. We developed PPLine, a Python-based proteogenomic pipeline providing …
the research of human proteome diversity, including rare variants. Liver tissues, HepG2
cells, and plasma were selected as one of the major objects for C-HPP studies. The
proteogenomic approach, a recently introduced technique, is a powerful method for
predicting and validating proteoforms coming from alternative splicing, mutations, and
transcript editing. We developed PPLine, a Python-based proteogenomic pipeline providing …
[引用][C] PPLine: An Automated Pipeline for SNP, SAP, and Splice Variant Detection in the Context of Proteogenomics
KG Sergeevich, DA Alexandrovich, KA Viktorovna… - 2015
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