Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction
Preeclampsia (PE) and fetal growth restriction (FGR) are both placenta-mediated disorders
with unclear pathogenesis. Metabolomics of maternal and fetal pairs might help in
understanding these disorders. We recruited prospectively pregnancies with normotensive
FGR, PE without FGR, PE+ FGR and uncomplicated pregnancies as controls. Nuclear
magnetic resonance metabolomics were applied on plasma samples collected at delivery.
Advanced lipoprotein, glycoprotein and choline profiling was performed using the Liposcale …
with unclear pathogenesis. Metabolomics of maternal and fetal pairs might help in
understanding these disorders. We recruited prospectively pregnancies with normotensive
FGR, PE without FGR, PE+ FGR and uncomplicated pregnancies as controls. Nuclear
magnetic resonance metabolomics were applied on plasma samples collected at delivery.
Advanced lipoprotein, glycoprotein and choline profiling was performed using the Liposcale …
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