Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans
S Bora, GSH Vardhan, N Deka, L Khataniar, D Gogoi… - Toxicology, 2021 - Elsevier
Paraquat (methyl viologen), is a non-selective contact herbicide and well known
mitochondrial toxicant. Mitochondria are the center of cellular metabolism, and involved in
the development, lifespan, and reproduction of an organism. Mitochondria are dynamic
organelles that are inherited maternally through the germline and carry multiple copies of
their own genome (mtDNA). It is important to understand the effects of acute and chronic
stress caused by mitochondrial toxicants over multiple generations at the cellular and …
mitochondrial toxicant. Mitochondria are the center of cellular metabolism, and involved in
the development, lifespan, and reproduction of an organism. Mitochondria are dynamic
organelles that are inherited maternally through the germline and carry multiple copies of
their own genome (mtDNA). It is important to understand the effects of acute and chronic
stress caused by mitochondrial toxicants over multiple generations at the cellular and …