Pathological implication of protein post-translational modifications in cancer

S Pan, R Chen - Molecular aspects of medicine, 2022 - Elsevier
Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and
their crosstalk is linked to many critical signaling events involved in neoplastic
transformation, carcinogenesis and metastasis. The pathological roles of various PTMs are
implicated in all aspects of cancer hallmark functions, cancer metabolism and regulation of
tumor microenvironment. Study of PTMs has become an important area in cancer research …
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