… mAbs might target epitopes with less evolutionary selection pressure to mutate in SARS-CoV-2 variants compared with neutralizing mAbs; they can be Fc engineered … Show full caption …
P Turelli, C Fenwick, C Raclot, V Genet, G Pantaleo… - bioRxiv, 2022 - biorxiv.org
… , Omicronvariants readily cause infections in individuals who have been either previously infected with other SARS-CoV-2variants or subjected to full … , conferredcomplete prophylactic …
PA Nikitin, JM DiMuzio, JP Dowling, NB Patel… - Science …, 2022 - science.org
… library of patient-derived antiviral antibodies (21), we identified three monoclonalantibodies (… 1C), the standalone IMM20184 antibody did not reach a completeneutralization of Omicron …
C Hérate, R Marlin, F Touret, N Dereuddre-Bosquet… - Heliyon, 2023 - cell.com
… Patient-derivedmonoclonalantibodyneutralizesSARS-CoV-2Omicronvariants and confers full … to prevent infection with SARS-CoV-2 (BQ.1.1 variant) following inoculation therefore it …
… Omicronvariant spike protein thus appear to confer broad … (B) Antibody binding footprints for the monoclonalantibodies … IS and ACM provided the vaccine-induced patient-derived sera …
… The BQ and XBB subvariants of SARS-CoV-2Omicron are now rapidly expanding, possibly … Monoclonalantibodies capable of neutralizing the original Omicronvariant were largely …
B Zhou, R Zhou, JFW Chan, M Luo, Q Peng, S Yuan… - bioRxiv, 2022 - biorxiv.org
… , Delta and Omicronvariantsconferred strong resistance to our … In these studies, patient-derived S2E12 and vaccine-induced … of recombinant monoclonalantibodies for the SARS-CoV-2 …
B Zhou, R Zhou, B Tang, JFW Chan, M Luo… - Nature …, 2022 - nature.com
… conferred by circulating SARS-CoV-2Omicronvariants. The … In these studies, patient-derived S2E12 and vaccine-induced … of recombinant monoclonalantibodies for the SARS-CoV-2 …
T Ozawa, Y Ikeda, L Chen, R Suzuki, A Hoshino… - Structure, 2024 - cell.com
… This approach circumvents the need for patient-derivedneutralizingantibodies, and may … binding activity and neutralizing activity against the Omicron BA.1 variant, we attempted to …