Peptide‐Functionalized Hydrogels: Peptide‐Functionalized Hydrogels Modulate Integrin Expression and Stemness in Adult Human Epidermal Keratinocytes (Adv …

D Davis‐Hall, V Nguyen, TJ D'Ovidio… - Advanced …, 2019 - Wiley Online Library
D Davis‐Hall, V Nguyen, TJ D'Ovidio, E Tsai, G Bilousova, CM Magin
Advanced Biosystems, 2019Wiley Online Library
Hydrogels that mimic the mechanical and biochemical properties of native human epidermis
improve stemness and proliferation of adult human epidermal keratinocytes. In article
number 1900022, Chelsea M. Magin and co-workers report increases in expression of β 1
integrins that maintain a stem-like ratio of keratin 14 (K14) to keratin 1 (K1) compared to
standard techniques over 14 days. These hydrogels could improve current techniques for
expanding cells ex vivo.
Hydrogels that mimic the mechanical and biochemical properties of native human epidermis improve stemness and proliferation of adult human epidermal keratinocytes. In article number 1900022, Chelsea M. Magin and co-workers report increases in expression of β 1 integrins that maintain a stem-like ratio of keratin 14 (K14) to keratin 1 (K1) compared to standard techniques over 14 days. These hydrogels could improve current techniques for expanding cells ex vivo.
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