… Despite the difficulty with categorization, the theme of redox sensing is conserved in Prdxs
… In summary, Prdxs can be regarded as the peroxide sensors of the cell, assessing peroxide …

… hydrogen peroxide (H2O2) and other organic peroxides to … interact with regulatory protein
factors like chaperones and kinases. These … For this reason, Prxs have sensing and regulatory …

… , this due to a variety of confounding factors, with quantitative and qualitative … peroxiredoxins,
as well as show differences in behaviour for peroxiredoxins 1 and 2 when exposed to H2O2 …

… without the help of many amazing people that are part of the … candidate for such a sensor is
the Peroxiredoxin/Sulfiredoxin … Instead of being resolved by thioredoxin, peroxiredoxins can …

… Cells have evolved an array of sensing mechanisms to protect themselves against …
transcription factors, such as STAT3 in mammalian cells and AP-1-like transcription factors in yeast, …

… is vast, we mainly focus on hydrogen peroxide (H 2 O 2 ) and … Multiple post-translational
modifications of peroxiredoxins … accumulation of the active transcription factor. The other hubs …

… Why should the cell make use of a peroxidase as a sensor and transmitter of H 2 O 2 -… Orp1
relays H 2 O 2 signals to the transcription factor Yap1, to activate its transcriptional activity. Its …

… different ways in which thiol peroxidases (peroxiredoxins) are … H 2 O 2 sensor protein, Hyper7,
directly coupled to different … the fungal AP-1-like transcription factor Yap1, triggering further …