Objective: To assess pharmacokinetic interaction of garlic with atorvastatin in dyslipidemic
rats. Materials and Methods: Sprague Dawley rats with induced dyslipidemia were divided
into five groups of eight rats each. Group 1 was given atorvastatin (10 mg/kg body weight (b.
wt) orally), group 2 was given atorvastatin (10 mg/kg b. wt orally)+ garlic (1% w/w in feed),
group 3 was maintained on atorvastatin (5 mg/kg b. wt orally)+ garlic (0.5% w/w in feed),
group 4 was maintained on atorvastatin (7.5 mg/kg b. wt orally)+ garlic (0.25% w/w in feed) …