Neuropeptides are responsible for the regulation of various biological activities and mediate various regulatory mechanisms associated with every organ system. They control and regulate communication between endocrine and nervous systems and are also involved in signaling between cells found in the central and peripheral nervous system. Certainly, they can modulate immunomodulation, neuroprotection, and physiological homeostasis (e.g., feeding behavior, balance of water, blood pressure, breakdown of glucose, cognition, stress response, and pain) by working as peptide hormones.