[引用][C] Pharmacology of the eosinophil

MA Giembycz, MA Lindsay - Pharmacological reviews, 1999 - ASPET

Pharmacological treatment of eosinophilic gastrointestinal disorders

S Hua, D Cook, MM Walker… - … of clinical pharmacology, 2016 - Taylor & Francis
… forms are eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis. Clinical
presentation depends on the affected GI site. Recently duodenal eosinophilia has been …

Systematic review with meta‐analysis: pharmacological interventions for eosinophilic oesophagitis

T Sawas, S Dhalla, M Sayyar… - … pharmacology & …, 2015 - Wiley Online Library
… decrease in eosinophil count less than baseline, <0–6 eos/hpf or 90% decrease in eosinophils
… the improvement in peak eosinophil count or percentage decrease in eosinophil count as …

Eosinophils as a pharmacological target for the treatment of allergic diseases

NAC Landolina, F Levi-Schaffer - Current Opinion in Pharmacology, 2014 - Elsevier
… is thought to prevent and/or limit irreversible organ damage and other eosinophil-… Several
eosinophil-targeted therapeutic agents which block specific steps in eosinophil differentiation, …

The effect of pharmacological PI3Kγ inhibitor on eotaxin-induced human eosinophil functions

Y Saito, M Takeda, J Nishikawa, Y Konno… - … Pharmacology & …, 2014 - Elsevier
… mice did not develop lung eosinophilia, although the detailed … eosinophilic inflammation
through CCR3. In this study, we tested the roles of PI3Kγ in eotaxin-induced eosinophil functions …

Eosinophil apoptosis as a therapeutic target in allergic asthma

P Ilmarinen, H Kankaanranta - Basic & clinical pharmacology & …, 2014 - Wiley Online Library
… by the accumulation of eosinophils into the lungs. Eosinophils release factors that damage
the … In the absence of any inflammatory survival‐prolonging factors, eosinophils die by …

Eosinophil diversity in asthma

G Van Hulst, HM Batugedara, J Jorssen, R Louis… - … Pharmacology, 2020 - Elsevier
… of eosinophils in asthma. Yet, a small but growing body of reports suggests that eosinophils
… that suggests the existence of eosinophil subsets with potentially distinct functional roles in …

Eotaxin and eosinophil recruitment: implications for human disease

SM Rankin, DM Conroy, TJ Williams, SM Rankin… - Molecular medicine …, 2000 - cell.com
… Using a guinea pig model of allergic airways disease, characterized by a marked lung
eosinophilia, we discovered an eosinophil chemoattractant in the bronchoalveolar lavage (BAL) …

Eosinophilic inflammation in allergic asthma

SS Possa, EA Leick, CM Prado, MA Martins… - … in pharmacology, 2013 - frontiersin.org
… in recruiting eosinophils to the lung during allergic inflammation. Once recruited, eosinophils
… response are related to reduction in eosinophil counts both in human and experimental …

IDENTIFICATION OF A HISTAMINE H4 RECEPTOR ON HUMAN EOSINOPHILS—ROLE IN EOSINOPHIL CHEMOTAXIS

M O'Reilly, R Alpert, S Jenkinson… - Journal of Receptors …, 2002 - Taylor & Francis
… human eosinophils were performed to investigate the pharmacology of the histamine
receptor on eosinophils which regulates histamine-induced chemotaxis. Eosinophil purification …