… In recent years, research on organophosphorus compounds, particularly phosphoramidates
… for the synthesis of phosphoramidates and phosphonamides by use of conventional …

… , and antiviral compounds), and veterinary (as anthelmintics). As an important class of …
compounds, this review provides an overview of phosphoramidate compounds covering …

… of aryloxy phosphoramidates of AZT with various para substituents and amino acids (14).33
These compounds … From this study, alanine phosphoramidate emerged as strikingly effective …

… Based on the primary metabolites obtained and from the known decomposition pathway of
aryl phosphoramidate derivatives, we propose a novel scheme for intracellular activation of …

… Other examples in which the ProTide technology showed a lack of significant improvement
of the antiviral activity versus the parent compounds are the phosphoramidates of 2-fluoro …

… of compound, especially within the pharmaceutical arena, this review discusses the most
significant examples of phosphoramidates … well as examples of selected compounds that act as …

… of phosphoramidates of 6-O-methyl-2′−β-C-methylguanosine as model compounds for
nucleosides having only the 5′-OH as reactive hydroxyl group, and phosphoramidates …

… In the hope of clarifying this situation, we have examined the reactivity of a series of
nucleophilic reagents toward phosphoramidate, which is not subject to the complication of …

… This review covers the main synthetic routes to and the corresponding mechanisms of
phosphoramidate formation. The synthetic routes can be separated into six categories: salt …

… reported SAR of phosphoramidates, we chose to focus … phosphoramidates may be related
to the relative stability of tertiary esters to enzyme-mediated hydrolysis. Comparing compound …