Natural antioxidants have the ability to protect organisms from damage caused by free radicalinduced oxidative stress. A lot of research has been carried out worldwide for finding natural antioxidants of plant origin. The present study was aimed to evaluate the phytochemical composition, total phenolic and flavonoid contents and antioxidant activity of P. cerasoides leaves. Extracts of P. cerasoides leaves were phytochemically examined for presence of different phytochemicals by standard methods. Total phenolic content of the various extracts was determined spectrometrically using Folin-Ciocalteu method, total flavonoid content by reported method and antioxidant efficacy by following DPPH radical scavenging protocol. Phytochemical screening showed the presence of alkaloids, steroids, terpenoids, flavonoids, phenolics, tannins, saponins, glycosides, carbohydrate, protein and amino acids in different extracts of P. cerasoides leaves. Methanol extract recorded the maximum number of chemical constituents. Presence of flavonoids and phenolic constituents were mostly found in extracts obtained with solvents of medium and high polarity. The total phenolic content (6.26±0.033 mg GAE/g of extract), total flavonoid content (3.86±0.016 mg QE/g of extract) and free radical scavenging (antioxidant) activity (IC50, 56.00±0.242 μg/ml) were highest in methanol extract. Total phenolic content had positive correlation with antioxidant capacity. The present study established leaves of P. cerasoides as rich sources of phenolic compounds and natural antioxidants. The study further provided scientific basis to traditional medicinal claims of the plant.