Pial synangiosis ameliorates movement disorders in the absence of prior stroke in moyamoya disease

S Greene, L Bansal, KA Coffman… - Journal of child …, 2016 - journals.sagepub.com
S Greene, L Bansal, KA Coffman, R Nardone, G Zuccoli
Journal of child neurology, 2016journals.sagepub.com
Background: Moyamoya disease is a rare cerebrovascular disease characterized by
progressive stenosis of the bilateral distal internal carotid arteries and their proximal
branches. Both chorea and dystonia have been reported as the initial presentation of
moyamoya disease. Objective: The objective was to define the clinical presentation and
describe the disease course following pial synangiosis of 3 patients with dyskinesias.
Methods: A retrospective chart review of 3 cases of patients presenting with movement …
Background
Moyamoya disease is a rare cerebrovascular disease characterized by progressive stenosis of the bilateral distal internal carotid arteries and their proximal branches. Both chorea and dystonia have been reported as the initial presentation of moyamoya disease.
Objective
The objective was to define the clinical presentation and describe the disease course following pial synangiosis of 3 patients with dyskinesias.
Methods
A retrospective chart review of 3 cases of patients presenting with movement disorders and ultimately diagnosed with moyamoya disease was performed.
Results
The authors present a case series of 1 patient with dystonia and 2 patients with chorea, all diagnosed with moyamoya disease. All patients experienced resolution of their movement disorders following pial synangiosis. Magnetic resonance imaging disclosed moyamoya disease-related basal ganglia anomalies in all patients.
Conclusions
Moyamoya disease is an important and surgically treatable cause of movement disorders.
Sage Journals
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