Pilot Scale Production of Single Cell Oil by Apiotrichum brassicae and Pichia kudriavzevii from Acetic Acid and Propionic Acid
L Burgstaller, L Oliver, T Dietrich, M Neureiter - Applied Sciences, 2023 - mdpi.com
Volatile fatty acids can be used as a cheap carbon source for biotechnological lipid
production with oleaginous yeasts, but one factor limiting their large-scale use is their
inherent cytotoxicity. Developing a suitable cultivation strategy can help mitigate the adverse
effect volatile fatty acids have, since these effects are strongly dependent on concentration
and pH. This work shows that, by employing a pH-stat fed-batch approach for the cultivation
of Apiotrichum brassicae V134 and Pichia kudriavzevii V194, lipid contents above 56 g/100 …
production with oleaginous yeasts, but one factor limiting their large-scale use is their
inherent cytotoxicity. Developing a suitable cultivation strategy can help mitigate the adverse
effect volatile fatty acids have, since these effects are strongly dependent on concentration
and pH. This work shows that, by employing a pH-stat fed-batch approach for the cultivation
of Apiotrichum brassicae V134 and Pichia kudriavzevii V194, lipid contents above 56 g/100 …
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