Platelet function in rheumatoid arthritis: arthritic and cardiovascular implications
AY Gasparyan, A Stavropoulos-Kalinoglou… - Rheumatology …, 2011 - Springer
Patients with rheumatoid arthritis (RA) are at high risk of cardiovascular events. Platelet
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular
and RA-associated factors can alter the structure and function of platelets, starting from
megakaryocytopoiesis. Reactive megakaryocytopoiesis increases circulating platelets count
and triggers hyperactivity. Hyperactive platelets target synovial membranes with subsequent
local rheumatoid inflammation. Hyperactive platelets interact with other cells, and target the …
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular
and RA-associated factors can alter the structure and function of platelets, starting from
megakaryocytopoiesis. Reactive megakaryocytopoiesis increases circulating platelets count
and triggers hyperactivity. Hyperactive platelets target synovial membranes with subsequent
local rheumatoid inflammation. Hyperactive platelets interact with other cells, and target the …
[PDF][PDF] Platelet Function in Rheumatoid Arthritis: Arthritic and Cardiovascular Implications
AY Gasparyan - researchgate.net
Patients with rheumatoid arthritis (RA) are at high risk of cardiovascular events. Platelet
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular
and RA-associated factors can alter the structure and function of platelets, starting from
megakaryocytopoiesis. Reactive megakaryocytopoiesis increases circulating platelets count
and triggers hyperactivity. Hyperactive platelets target synovial membranes with subsequent
local rheumatoid inflammation. Hyperactive platelets interact with other cells, and target the …
biomarkers are involved in inflammation, atherosclerosis and thrombosis. Cardiovascular
and RA-associated factors can alter the structure and function of platelets, starting from
megakaryocytopoiesis. Reactive megakaryocytopoiesis increases circulating platelets count
and triggers hyperactivity. Hyperactive platelets target synovial membranes with subsequent
local rheumatoid inflammation. Hyperactive platelets interact with other cells, and target the …
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