… of talin1 in both the development and maintenance of the glomerular filtration barrier and report
that talin1 … Precisely how talin1 contributes to the formation and maintenance of podocyte …

… The glomerular filtration barrier is a highly complex structure, … and maintenance of the
glomerular filtration barrier. Human … These data show that talin-1, a protein known to be important …

… kidney glomerular filtration barrier. The interface between the podocyte and the glomerular
… The large cytoskeletal protein talin1 is not only pivotal for integrin activation, but also directly …

… are crucial for maintaining the integrity of this barrier; … filtration barrier in specific ways
and particularly emphasises the role of vinculin in the maintenance of the glomerular barrier in …

… of the integrity of the glomerular filtration barrier. Podocyte actin … Given the critical role that
nephrin plays in maintenance of the … calpain-induced cleavage of talin1 which also results in …

… suggest a critical role for … maintenance of the glomerular filtration barrier. The loss of key
molecular machinery results in defective actin regulation and faulty slit diaphragm maintenance, …

… Tian et al., Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
… to maintain the kidney filtration barrier. Proc Natl Acad Sci USA. 114, E4621-E4630 (2017). …

… important roles in the podocyte-GBM interaction and maintenance of the glomerular filtration
barrier… molecules, such as integrin-linked kinase, talin1, and CD151, are similar to those …

… , and Cdc42), and podocyte-associated talins. The second … tightly to maintain the intact of
glomerular filtration barrier. Any … the importance of talin1 in the field of kidney disease for the …

… and the maintenance of the filtration barrier [23, 24]. … and is critical in maintaining the
glomerular filtration barrier [39]. … to phosphorylate talin-1 at T152 in Drosophila and is crucial for …