Polyethylenimine-associated cerium oxide nanoparticles: a novel promising gene delivery vector
Aims The development of highly efficient and low toxic non-viral gene delivery vectors is the
most challenging issues for successful application of gene therapy. A particular focus has
been on understanding structure-activity relationships for transfection activity and toxicity of
polyethylenimine (PEI). During the last decade, the use of cerium oxide nanoparticles (CeO
2-NPs) in biomedicine has attracted much attention due to their pH-dependent antioxidant
activity. CeO 2-NPs provide protection normal cells from various forms of reactive oxygen …
most challenging issues for successful application of gene therapy. A particular focus has
been on understanding structure-activity relationships for transfection activity and toxicity of
polyethylenimine (PEI). During the last decade, the use of cerium oxide nanoparticles (CeO
2-NPs) in biomedicine has attracted much attention due to their pH-dependent antioxidant
activity. CeO 2-NPs provide protection normal cells from various forms of reactive oxygen …
[引用][C] Polyethylenimine-associated cerium oxide nanoparticles: A novel promising gene delivery vector
RK Oskuee, L Hasanzadeh, M Darroudi… - 2019
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