Possible role of nitric oxide (NO) in the regulation of gender related differences in stress induced anxiogenesis in rats

A Chakraborti, K Gulati, A Ray - Nitric oxide, 2014 - Elsevier
Gender related differences in stress induced neurobehavioral disorders have been reported
although the mechanisms involved are not yet clear. The present study investigated the role
of nitric oxide, an important biomodulator in the sex related differences in stress induced
anxiety like behavior in rats. Restraint stress (RS for 1 h) was used as the experimental
stressor and the effects of NO modulators were assessed in the elevated plus maze (EPM)
test in both male and female rats. No metabolites (NOx) and asymmetric dimethyl arginine …
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