Potential role of curcumin and garlic acid against diazinon and propoxur hepatotoxicity

M Waly, HA El-Mezayen, M Mohyee - Int. J. Pharm. Sci. Rev. Res, 2015 - hero.epa.gov
Diazinon, an organophosphorus insecticide and propoxur, a carbamate insecticide have
been used in agriculture and public health for several years. The aim of the present study
was to evaluate the oxidative stress caused by the two insecticides and biochemical
changes in adult male Wistar rats and to evaluate the protective effect of curcumin and
garlic. Diazinon (10 mg/kg per day in corn oil), propoxur (10 mg/kg per day in corn oil) alone
or with curcumin (100 mg/kg per day in corn oil) and/or garlic (20 mg/kg per day in distilled …
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