Predicting carriers of ongoing selective sweeps without knowledge of the favored allele

R Ronen, G Tesler, A Akbari, S Zakov… - PLoS …, 2015 - journals.plos.org
Predicting Carriers of Ongoing Selective Sweeps) to identify carriers of the favored allele in
selective sweepssweeps, as well as on data from well-known sweeps in human populations. …

[PDF][PDF] Predicting Carriers of Ongoing Selective Sweeps Without Knowledge of the Favored Allele—Supporting Information

R Ronen, G Tesler, A Akbari, S Zakov, NA Rosenberg… - stanford.edu
… The coalescence of a sample of n individuals to their most recent common ancestor MRCAall,
during a hard sweep. We assume that the current time has νn carriers of the favored allele. …

Haplotype Allele Frequency (HAF) score: predicting carriers of ongoing selective sweeps without knowledge of the adaptive allele

R Ronen, G Tesler, A Akbari, S Zakov… - … on Research in …, 2015 - Springer
carriers of the adaptive allele in selective sweeps, and we demonstrate its power on simulations
of both hard and soft selective sweeps… We focus on instances where the favored allele is …

[PDF][PDF] Versatile detection of diverse selective sweeps with flex-sweep

ME Lauterbur, K Munch, D Enard - Molecular Biology and …, 2023 - academic.oup.com
… We typically do not know what type(s) of sweeps to expect during a targeted analysis …
Predicting carriers of ongoing selective sweeps without knowledge of the favored allele. PLoS …

Two-dimensional site frequency spectrum for detecting, classifying and dating incomplete selective sweeps

Y Satta, W Zheng, KV Nishiyama, RL Iwasaki… - Genes & genetic …, 2019 - jstage.jst.go.jp
allelic variability (IAV) maintained within a derived allele (D) group that has undergone an
incomplete selective sweep against an ancestral allele … E ζ or K ζ without knowing the accurate …

Correction: Predicting Carriers of Ongoing Selective Sweeps without Knowledge of the Favored Allele

R Ronen, G Tesler, A Akbari, S Zakov… - Plos …, 2016 - journals.plos.org
… Genealogies of three samples (n = 6) progressing through a selective sweep, from left to
right. Neutral mutations are shown as red circles, and are numbered in red; the favored …

Fine-mapping the favored mutation in a positive selective sweep

A Akbari, JJ Vitti, A Iranmehr, M Bakhtiari, PC Sabeti… - bioRxiv, 2017 - biorxiv.org
… Because of the separation between carriers and non-carriers, the HAF-scores can be used
to predict the carrier of ongoing selective sweeps without knowledge of the favored allele 6 . …

New insights into the genetic basis of Monge's disease and adaptation to high-altitude

T Stobdan, A Akbari, P Azad, D Zhou… - Molecular biology …, 2017 - academic.oup.com
… of selective sweeps, including differences in allele frequency … an ongoing selective sweep,
without knowledge of the favoredpredicted 37 out of 188 haplotypes to be carriers of the …

Learning natural selection from the site frequency spectrum

R Ronen, N Udpa, E Halperin, V Bafna - Genetics, 2013 - academic.oup.com
… We consider the case of a selective sweep, where a single (de … As a result, the frequency
of the favored allele and of those … be applied without a priori knowledge of these parameters. …

TRPV6 as a putative genomic susceptibility locus influencing racial disparities in cancer

PA Francis-Lyon, F Malik, X Cheng, A Ghezavati… - Cancer Prevention …, 2020 - AACR
knowledge, however, an investigation of association between the germline TRPV6 and
cancer in subjects of African ancestry has not … as the carrier of the favored allele in positive …