A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer

CS Zhu, PF Pinsky, DW Cramer, DF Ransohoff… - Cancer prevention …, 2011 - AACR
… A panel of biomarkers may improve predictive performance over individual markers.
Although many biomarker panels have been described for ovarian cancer, few studies used …

Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel

K Oikonomopoulou, L Li, Y Zheng, I Simon… - … journal of cancer, 2008 - nature.com
biomarkers for ovarian cancer prognosis or prediction of therapeutic response. The objective
of this study was to examine a panel of … and survival of ovarian cancer patients. Sera from …

Multi-biomarker panel signature as the key to diagnosis of ovarian cancer

T Muinao, HPD Boruah, M Pal - Heliyon, 2019 - cell.com
… stage detection of ovarian cancer. Overall, this review demonstrates a panel of biomarkers
signature as … ) for prediction of ovarian cancer in women with pelvic mass. Sensitivities for this …

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

MR Russell, C Graham, A D'Amato… - … journal of cancer, 2019 - nature.com
… as a probability in the range 0–1; finally, the risk classification is determined from a table
of thresholds based on the positive predictive value associated with the probability score. …

Evaluation of biomarker panels for early stage ovarian cancer detection and monitoring for disease recurrence

LJ Havrilesky, CM Whitehead, JM Rubatt, RL Cheek… - Gynecologic …, 2008 - Elsevier
… In monitoring evaluation of 27 patients who experienced recurrence of OC, sensitivity for
predicting recurrence was 100% for the biomarker panel and 96% for CA125. At least one of the …

New predictive biomarkers for ovarian cancer

GA Atallah, NH Abd. Aziz, CK Teik, MN Shafiee… - Diagnostics, 2021 - mdpi.com
ovarian cancer, ovarian signalling pathway, ovarian cancer diagnosis and prognosis, and
current and/or new ovarian cancer biomarkers, … a panel of 28 immunosoluble biomarkers from …

Multiple biomarker panels for early detection of ovarian cancer

ZR Yurkovetsky, FY Linkov, DE Malehorn… - Future …, 2006 - Taylor & Francis
… with a sensitivity of 95%, a PPV of 95%, a specificity of 95% and a negative predictive
value of 94% [62]. In this study, sera from 106 healthy women and 100 patients with epithelial …

Potential markers for detection and monitoring of ovarian cancer

BJD Rein, S Gupta, R Dada, J Safi… - Journal of …, 2011 - Wiley Online Library
… to discover new biomarkers of ovarian cancer in order to … specificity and positive predictive
value for ovarian cancer, noting … low within biomarker panels from the addition of this marker, …

A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma

C Han, S Bellone, ER Siegel, G Altwerger… - Gynecologic …, 2018 - Elsevier
prediction models have been developed to detect ovarian … as an important biomarker in
early detection of ovarian cancer. … 4-marker panel shows better performance in early ovarian

Biomarker testing for ovarian cancer: clinical utility of multiplex assays

BM Nolen, AE Lokshin - Molecular diagnosis & therapy, 2013 - Springer
… an SP of 74.9 % with a negative predictive value (NPV) of 98 %. … ovarian cancer has produced
a number of biomarker panels offering levels of SN and SP exceeding 90 %; these panels