[HTML][HTML] Predictive value of serum myoglobin and creatine phosphokinase for development of acute kidney injury in traumatic rhabdomyolysis

NA Raju, SV Rao, JC Joel, GG Jacob… - Indian journal of …, 2017 - ncbi.nlm.nih.gov
NA Raju, SV Rao, JC Joel, GG Jacob, AK Anil, SM Gowri, S Kandasamy
Indian journal of critical care medicine: peer-reviewed, official …, 2017ncbi.nlm.nih.gov
Results: Fourteen out of 90 patients developed AKI and one patient required renal
replacement therapy. CPK value of> 12,000 U/l was identified to have 64% sensitivity and
56% specificity for developing AKI whereas serum myoglobin value of> 5000 ng/ml was
identified to have 78% sensitivity and 77% specificity for developing AKI. Conclusion:
Following traumatic RM, in patients on “crush protocol,” serum myoglobin is a more sensitive
and specific test than serum CPK, for predicting AKI.
Results:
Fourteen out of 90 patients developed AKI and one patient required renal replacement therapy. CPK value of> 12,000 U/l was identified to have 64% sensitivity and 56% specificity for developing AKI whereas serum myoglobin value of> 5000 ng/ml was identified to have 78% sensitivity and 77% specificity for developing AKI.
Conclusion:
Following traumatic RM, in patients on “crush protocol,” serum myoglobin is a more sensitive and specific test than serum CPK, for predicting AKI.
ncbi.nlm.nih.gov
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